BPC-157 is a synthetic peptide derived from a protein found in gastric juice. In the repair literature it is best known for work on tissue and tendon healing, gastrointestinal protection and recovery models.
PEPTIDE · RESEARCH MONOGRAPH · SYNTHETIC PENTADECAPEPTIDE (15 AMINO ACIDS)
Mechanisms described in the published preclinical literature.
BPC-157 has been reported to upregulate vascular endothelial growth factor expression, associated with new vessel formation and blood supply to injured tissue in preclinical models.
Published work reports increased growth hormone receptor expression in tendon fibroblasts, on the order of sevenfold within three days, discussed as part of tissue repair signalling.
Cytoprotective properties have been described across several organ systems in animal studies, with most attention on gastrointestinal and musculoskeletal tissue.
Findings from the published literature, as the studies reported them. Where a finding comes from a human trial, it says so. None is a claim about the material supplied here.
Faster healing of Achilles tendon, medial collateral ligament and rotator cuff injuries in rat models, with improved collagen fibre organisation.
Chang et al. 2014
Cytoprotective effects against NSAID-induced damage, alcohol lesions and inflammatory bowel disease models.
Sikiric et al. 2011
Neuroprotective effects reported in traumatic brain injury and peripheral nerve damage models, with improved recovery markers.
Sikiric et al. 2016
Angiogenesis and accelerated vessel healing after surgical transection in animal models, via nitric oxide system modulation.
Sikiric et al. 2019
BPC-157 is a synthetic pentadecapeptide, a chain of fifteen amino acids, derived from a partial sequence of body protection compound, a protein identified in gastric juice. It is produced by solid-phase synthesis rather than extracted from tissue.
No. It is not an approved drug and has not been evaluated by the FDA for any use. It is supplied strictly as a reference material for in-vitro laboratory research.
Published preclinical work spans tendon and ligament healing, gastrointestinal cytoprotection, angiogenesis via the VEGF and nitric oxide pathways, and neuroprotection. These are animal and in-vitro findings, not human clinical outcomes.
It is supplied lyophilised and reconstituted with bacteriostatic water before use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.
This material is not a drug, food, cosmetic or medical device. It is not intended for human or veterinary consumption, therapeutic use, diagnostic application or any in-vivo use. Safety data for human exposure has not been established.
Store the sealed vial at −20°C for long-term stability. Once reconstituted, hold at 2–8°C and protect from light; we do not publish an in-use shelf life for reconstituted material because we have not measured one on this material. Protect from light and avoid repeated freeze-thaw cycles.
Each entry opens a PubMed search for that title rather than a fixed identifier, so the link resolves to the current record.
For laboratory research use only. Not a drug, supplement or medical product, and not for human or animal use. Every finding referenced on this page comes from published preclinical or laboratory research and is not a claim about this product.
