Lyophilised powder · 99%+ documented HPLC
Naturally occurring copper-binding tripeptide studied in dermal-signalling and remodelling models.
$39.99per 50mg vial
Figures are structural data from our specification and certificates, or are drawn from published third-party literature about the compound, and are provided for orientation only. Nothing here is a claim about what this material does. Supplied for laboratory research use only.
GHK-Cu is a copper-binding tripeptide (glycyl-L-histidyl-L-lysine) complexed with copper(II). It occurs naturally in human plasma and has been studied extensively in relation to extracellular matrix remodelling. Its characteristic deep blue colour comes from the copper complex.
C14H24N6O4 · Cu · composition, not conformation
Signalling pathways examined in preclinical models. Descriptive of published research directions, not claims of effect.
Studied in relation to collagen and glycosaminoglycan synthesis in dermal fibroblast cultures, and to the balance of matrix metalloproteinases and their inhibitors.
Explored in oxidative-stress endpoints, where the copper-bound form rather than the free peptide is the species examined.
The tripeptide's affinity for copper(II) is the basis of much of its characterisation; both the peptide purity and the copper stoichiometry are assayed on every lot we release.
Isolated from human plasma as a naturally occurring factor affecting how cells grow.
Binds copper(II) readily, and the copper-bound form is what the research examines.
Studied topically on impaired-healing skin and on the enzymes that remodel wound tissue.
Reference class characteristics for orientation. Half-life figures are typical literature values, not lot measurements.
| Compound | Receptor class | Typical half-life | Note |
|---|---|---|---|
| GHK-Cu | Tripeptide-Cu | Short | ECM remodelling |
| BPC-157 | Pentadecapeptide | Short | Cytoprotection |
| TB-500 | Tβ4 fragment | Longer | Actin regulation |
Milestones in the study of this compound class.
Isolated from human plasma by Pickart and Thaler and identified as a factor altering how cells grow.
Copper-binding form characterised as the species the research examines.
Studied topically on impaired-healing skin and the enzymes that remodel wound tissue.
Reviewed as a modulator of multiple cellular pathways in skin regeneration.
Every lot is documented by an independent laboratory. The newest lot appears first.
| Lot | Reported | Size | HPLC | Laboratory | Certificate |
|---|---|---|---|---|---|
| GHK100-052026-4 | 14 May 2026 | 100mg | 99.86% | Freedom Diagnostics | View |
| 8ZVN1B | 24 Jun 2026 | 50mg | 99.95% | Freedom Diagnostics | View |
| GHK100-042026-2 | 22 Apr 2026 | 100mg | 99.90% | Freedom Diagnostics | View |
| GHK100-032026-4 | 11 Mar 2026 | 100mg | 99.786% | Freedom Diagnostics | View |
| C3M9KQ | 12 May 2026 | 50mg | 99.75% | Freedom Diagnostics | View |
| GHK50-02062026-J | 11 Feb 2026 | 50mg | 99.538% | Freedom Diagnostics | View |
| GHK100-032026-1 | 25 Mar 2026 | 100mg | 99.634% | Freedom Diagnostics | View |
| 900001 | 20 Feb 2026 | 50mg | 99.79% | Freedom Diagnostics | View |
99.86%
HPLC purity
The signed PDF is the full certificate. The accession and search code above resolve the same record at the laboratory.
HPLC purity
RP-HPLC, 214 nm
Identity
LC-MS
Lot GHK100-052026-4
This material is supplied as a reference standard for in-vitro laboratory research only. It has not been evaluated by the FDA, is not a drug, and is not intended for human or veterinary use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.
Every lot is released against a ≥99% specification by reversed-phase HPLC. Released lots have measured between 99.538% and 99.95%; the figure for the lot you receive is printed on its certificate rather than quoted as a range.
Yes — one per lot, signed by the testing laboratory, with the lot number, the HPLC result, identity confirmation and the measured net peptide content. All eight are published in the COA library, including for lots no longer in stock.
50mg and 100mg vials.
Glycyl-L-histidyl-L-lysine — three residues, Gly-His-Lys — complexed with copper(II) at 1:1. Identity is confirmed lot-by-lot against a certified reference standard by LC-MS, and that confirmation is what the certificate reports.
The colour comes from the copper(II) ion coordinated by the tripeptide, and every certificate we hold records the appearance as blue lyophilised powder. A pale or colourless lot would indicate incomplete complexation, which is why copper stoichiometry is assayed alongside peptide purity.
Store the sealed vial at −20°C for long-term stability and 2–8°C for short-term handling. Protect from light and avoid repeated freeze-thaw cycles. Compound-specific stability data is printed on the certificate of analysis supplied with the lot.
Independent published research relating to this compound. Listed for reference; Serviam Bio Labs is not affiliated with these authors and makes no claims based on their findings.
Tripeptide in human serum which prolongs survival of normal liver cells
Pickart L, Thaler MM · 1973 · Biochemical and Biophysical Research Communications
discoveryCopper tripeptide in impaired wound healing
Parker A et al. · 2013 · Otolaryngology-Head and Neck Surgery
repairGHK peptide as a natural modulator of multiple cellular pathways
Pickart L et al. · 2012 · BioMed Research International
Regenerative and protective actions of the GHK-Cu peptide
Pickart L, Margolina A · 2018 · Int J Molecular Sciences
The full reference entry: molecular data, the mechanisms described in the literature, what the research covers, the specification and the papers behind it.
For laboratory research use only. All compounds listed on this site are sold strictly as reference materials for in-vitro laboratory research conducted by qualified professionals. They are not drugs, foods, cosmetics, or medical devices. They are not intended for human or veterinary consumption, therapeutic use, diagnostic application, or any in-vivo use whatsoever. These statements have not been evaluated by the Food and Drug Administration. By purchasing, you affirm that you are a qualified researcher and that you will comply with all applicable institutional, local, state and federal regulations governing the handling of research chemicals.
