GLP-1 receptor agonism
Single-receptor engagement makes this the reference point against which dual and triple agonists are compared.
- GLP-1 receptor
- Class benchmark
RP-HPLC · 214nm
99%+ HPLCPASS
- Molecular formula
- C187H291N45O59
- Molecular weight
- 4113.58 g/mol
- CAS / identifier
- 910463-68-2
- Appearance
- White lyophilised powder
- Solubility
- Soluble in bacteriostatic water
- Storage
- -20°C long term, protect from light
- Purity
- 99%+ by RP-HPLC, 214 nm
- Identity
- Conforms (reference match)
- Ships from
- United States
Lyophilised powder · 99%+ documented HPLC
Ships from USAView COA
GLP-1 Peptide
Long-acting GLP-1 receptor agonist widely used as a reference compound in metabolic research.
$79.99per 15mg vial
Vial size
15mg$79.99$5.33/mg
1
Purity 99%+RP-HPLC documented
Identity conformsreference standard match
- Ships from the US
- Discreet packaging
- Free shipping over $250
- 31
- Amino acid residues in the backbone.
- C18
- Fatty diacid chain on the lysine at position 26, the acylation behind its long half-life.
- 99%+
- Documented HPLC purity, lot by lot.
- 3rd-party
- Independently assayed.
Figures are structural data from our specification and certificates, or are drawn from published third-party literature about the compound, and are provided for orientation only. Nothing here is a claim about what this material does. Supplied for laboratory research use only.
01About this compound
What GLP-1 is
GLP-1 is a long-acting GLP-1 receptor agonist and a benchmark reference compound across metabolic research. Structural acylation confers an extended half-life widely characterised in PK models. Supplied lyophilised and documented lot-by-lot.
- Receptor class
- GLP-1
- Residues
- 31
- Typical half-life
- ~7 days (class literature)
- Form
- Lyophilised powder
- Presentation
- 15mg vial
Sequence
- GLP
- 1 receptor agonist
- acylated
BACKBONE IMPRESSION · NOT A STRUCTURAL MODEL
Atomic composition
582atoms
- 187
- 291
- 45
- 59
C187H291N45O59 · composition, not conformation
02MechanismHow GLP-1
How GLP-1
has been studied.
Signalling pathways examined in preclinical models. Descriptive of published research directions, not claims of effect.
Acylation and half-life
A fatty-acid chain extends circulating half-life to roughly a week in the models characterised in the literature.
- Long circulating half-life
- Albumin binding
Appetite-signalling models
Central appetite-signalling pathways are the most-referenced mechanism in the published research base.
- Central signalling
- Energy intake
03Uses & applications
What GLP-1 is researched for
Metabolic research
Class reference
The most widely referenced single-incretin comparator in metabolic protocols.
Pharmacokinetics
Half-life engineering
Used where acylation-driven half-life extension is the property under study.
04Class comparison
How it compares in its class
Reference class characteristics for orientation. Half-life figures are typical literature values, not lot measurements.
| Compound | Receptor class | Typical half-life | Note |
|---|---|---|---|
| GLP-1 | GLP-1 | ~7 days | Long-acting standard |
| GLP-3 RT | GIP+GLP-1+GCG | ~6 days | Triple agonist |
| GLP-1 L | GLP-1 | ~13 h | Daily reference |
| GLP-1 E | GLP-1 | ~2.4 h | Short-acting |
05Selectivity
Selectivity profile
A multi-axis orientation profile. Relative, not absolute affinity data.
GLP-1
- GLP-1
- 8294
- Half-life
- 8890
- Selectivity
- 7895
- Solubility
- 7072
- Stability
- 8488
Axes are normalised 0 to 100 for comparison. These are directional summaries of published class data, not measured binding constants for this lot.
06Pharmacokinetics
Illustrative PK decay
A relative plasma-concentration model over time, normalised so the peak reads 100.
GLP-1
Illustrative. A typical profile for the compound class, not a measured result for this product.
07Research history
Class research timeline
Milestones in the study of this compound class.
- 2012
Acylated long-acting GLP-1 analogue characterised in the PK literature.
- 2016
Receptor-binding reference data established for the class.
- 2019
Oral-formulation research broadens the reference dataset.
- 2023
Widely used as a single-receptor comparator in incretin research.
08Documentation
Certificates of analysis
Every lot is documented by an independent laboratory. The newest lot appears first.
| Lot | Reported | Size | HPLC | Laboratory | Certificate |
|---|---|---|---|---|---|
| GS20-032026-1 | 22 May 2026 | 20mg | 99.689% | Freedom Diagnostics | View |
Newest lot
99.689%
HPLC purity
- Lot
- GS20-032026-1
- Released to sale
- 22 May 2026
- Size
- 20mg
- Identity
- Conforms (reference match)
- Content
- 23.85mg
- Appearance
- White lyophilised powder
- Laboratory
- Freedom Diagnostics
The signed PDF is the full certificate. The accession and search code above resolve the same record at the laboratory.
09Third-party verifiedIndependently tested.
Independently tested.
Verifiably pure.
- PASS
HPLC purity
RP-HPLC, 214 nm
- CONFIRMED
Identity
LC-MS
Certificate of analysis
PASSLot GS20-032026-1
RP-HPLC · 214nm22 May 2026
- HPLC purity
- 99.689%
- Identity
- Conforms (reference match)
- Laboratory
- Freedom Diagnostics
- Net content
- 23.85mg
10Full specification
Every field on the label
- Sequence
- GLP-1 receptor agonist · acylated
- Molecular formula
- C187H291N45O59
- Molecular weight
- 4113.58 g/mol
- CAS / identifier
- 910463-68-2
- Quantity per vial
- 15 mg
- Purity
- 99.689% by RP-HPLC, 214 nm
- Identity
- Conforms (reference match)
- Appearance
- White lyophilised powder
- Solubility
- Soluble in bacteriostatic water
- Storage
- -20°C long term, protect from light
- Ships from
- United States
- Lot
- GS20-032026-1
- Assay date
- 22 May 2026
This material is supplied as a reference standard for in-vitro laboratory research only. It has not been evaluated by the FDA, is not a drug, and is not intended for human or veterinary use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.
Every lot is released against a ≥99% specification by reversed-phase HPLC. The released lot measured 99.689%; the figure for the lot you receive is printed on its certificate rather than quoted as a range.
Yes — one per lot, signed by the testing laboratory, with the lot number, the HPLC result, identity confirmation and the measured net peptide content. Every certificate we hold is published in the COA library, including for lots no longer in stock.
A single 15mg vial. The certificate on file is for a 20mg fill because the same material is released in bulk sizes for wholesale; that lot appears in the certificate table but is not sold on this page.
A 31-residue backbone carrying a C18 diacid chain on the lysine at position 26, which is the acylation responsible for the extended half-life. Identity is confirmed lot-by-lot against a certified reference standard by LC-MS, and that confirmation is what the certificate reports.
12Cited sources
Published literature
Independent published research relating to this compound. Listed for reference; Serviam Bio Labs is not affiliated with these authors and makes no claims based on their findings.
- [1]
Acylation and half-life engineering of GLP-1 analogues
Lau J. et al. · 2015 · Journal of Medicinal Chemistry
pk - [2]
GLP-1 receptor selectivity and signalling
Class literature · 2017 · Endocrinology
binding - [3]
Central appetite-signalling models of GLP-1 agonism
Class literature · 2019 · Cell Metabolism
mechanism
Research library
The evidence behind this page
For laboratory research use only. All compounds listed on this site are sold strictly as reference materials for in-vitro laboratory research conducted by qualified professionals. They are not drugs, foods, cosmetics, or medical devices. They are not intended for human or veterinary consumption, therapeutic use, diagnostic application, or any in-vivo use whatsoever. These statements have not been evaluated by the Food and Drug Administration. By purchasing, you affirm that you are a qualified researcher and that you will comply with all applicable institutional, local, state and federal regulations governing the handling of research chemicals.