Lyophilised powder · 99%+ documented HPLC
Synthetic analog of human growth-hormone-releasing hormone, N-terminally modified for stability against enzymatic degradation.
$99.99per 10mg vial
Figures are structural data from our specification and certificates, or are drawn from published third-party literature about the compound, and are provided for orientation only. Nothing here is a claim about what this material does. Supplied for laboratory research use only.
Tesamorelin is a stabilised 44-residue analog of growth hormone-releasing hormone, modified at the N-terminus with a trans-3-hexenoyl group that resists enzymatic cleavage. It is the longest peptide in this catalogue, which makes it a useful characterised standard for analytical methods on large peptides.
C221H366N72O67S · composition, not conformation
Signalling pathways examined in preclinical models. Descriptive of published research directions, not claims of effect.
Binds the pituitary GHRH receptor to stimulate endogenous growth hormone release, which preserves the body's own pulsatile release pattern rather than overriding it the way administered growth hormone does.
Growth hormone released downstream of the GHRH receptor activates hormone-sensitive lipase in adipocytes, the signalling route described in the class literature.
The trans-3-hexenoyl modification at the N-terminus is the structural feature responsible for improved resistance to dipeptidyl peptidase cleavage, and the reason a native GHRH sequence becomes usable.
Used as a full-length GHRH analog reference in endocrine signalling work on the growth hormone axis.
Valuable as a characterised standard when developing methods for peptides above 40 residues.
Reference class characteristics for orientation. Half-life figures are typical literature values, not lot measurements.
| Compound | Receptor class | Typical half-life | Note |
|---|---|---|---|
| Tesamorelin | GHRH analog | Short | Full-length GHRH analog |
| Ipamorelin | GHS-R1a agonist | Short | Selective GH release |
| MOTS-C | Mitochondrial-derived peptide | Short | AMPK activation |
Every lot is documented by an independent laboratory. The newest lot appears first.
| Lot | Reported | Size | HPLC | Laboratory | Certificate |
|---|---|---|---|---|---|
| TESM-052026-4 | 14 May 2026 | 10mg | 99.87% | Freedom Diagnostics | View |
| TESM-042026-4 | 23 Apr 2026 | 10mg | 99.93% | Freedom Diagnostics | View |
| AV2C30 | 12 May 2026 | 10mg | 99.93% | Freedom Diagnostics | View |
| TESM12172025-J | 20 Dec 2025 | 10mg | 99.413% | Freedom Diagnostics | View |
| NWPBJ4 | 11 Mar 2026 | 10mg | 99.253% | Freedom Diagnostics | View |
99.87%
HPLC purity
The signed PDF is the full certificate. The accession and search code above resolve the same record at the laboratory.
HPLC purity
RP-HPLC, 214 nm
Identity
LC-MS
Lot TESM-052026-4
This material is supplied as a reference standard for in-vitro laboratory research only. It has not been evaluated by the FDA, is not a drug, and is not intended for human or veterinary use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.
Every lot is documented at 99%+ by RP-HPLC with identity confirmed by LC-MS, run by an independent laboratory. Released lots have measured between 99.253% and 99.93%; the figure for the lot you receive is in the certificate table above.
Yes. Every lot ships with its own signed certificate, and all five are published in the COA library, including for lots no longer in stock.
10mg and 20mg vials. The certificates on file are 10mg lots.
trans-3-hexenoyl-GRF(1-44)-NH2 — the full 44-residue growth hormone-releasing hormone sequence, acylated at the N-terminus and amidated at the C-terminus. Note that the residue count is stated as 6 in some published summaries; 44 is what the formula C221H366N72O67S corresponds to.
At 44 residues it is by a wide margin the longest peptide in our catalog. Synthesis yield falls and purification difficulty rises sharply with chain length, which is reflected in the price.
Store the sealed vial at −20°C for long-term stability and 2–8°C for short-term handling. Protect from light and avoid repeated freeze-thaw cycles. Compound-specific stability data is printed on the certificate of analysis supplied with the lot.
Independent published research relating to this compound. Listed for reference; Serviam Bio Labs is not affiliated with these authors and makes no claims based on their findings.
The full reference entry: molecular data, the mechanisms described in the literature, what the research covers, the specification and the papers behind it.
For laboratory research use only. All compounds listed on this site are sold strictly as reference materials for in-vitro laboratory research conducted by qualified professionals. They are not drugs, foods, cosmetics, or medical devices. They are not intended for human or veterinary consumption, therapeutic use, diagnostic application, or any in-vivo use whatsoever. These statements have not been evaluated by the Food and Drug Administration. By purchasing, you affirm that you are a qualified researcher and that you will comply with all applicable institutional, local, state and federal regulations governing the handling of research chemicals.
